Birth-acquired herpes Health Article

Definition

Birth-acquired herpes is a herpes virus infection that an infant gets (acquires) at the time of birth.

Alternative Names

HSV; Congenital herpes; Herpes - congenital

Causes, incidence, and risk factors

Newborn infants can become infected with herpes virus:

• In the uterus (intrauterine herpes -- this is very rare)
• Passing through the birth canal (birth-acquired herpes, the most common method of infection)
• Right after birth (postpartum)

If the mother has an active genital herpes infection at the time of delivery, the baby is more likely to become infected during birth. Some mothers are not aware when they have internal (inside the vagina) herpes sores, so it is important for women to tell their doctor if they have a history of genital herpes.

In addition, some people have had herpes infections in the past, but were not aware of it and were never diagnosed or treated. These people, not knowing that they have herpes, may pass it to their baby. Herpes type 2 (genital herpes) is the most common cause of herpes infection in newborn babies, but herpes type 1 (oral herpes) can also occur.

Symptoms

Intrauterine herpes can cause:

• Eye disease, such as inflammation of the retina (chorioretinitis)
• Severe brain damage
• Skin lesions

Birth-acquired herpes can produce localized (in one area of the body) or systemic (throughout the body) disease. Infants may develop only a localized skin infection consisting of small fluid-filled blisters (vesicles) that rupture, crust over, and finally heal, often leaving a mild scar.

A second type of birth-acquired herpes infection leads to encephalitis, an inflammation of the brain that can result in seizures and later brain and nervous system (neurologic) problems. If untreated, it may lead to death.

Disseminated herpes infection is the most dangerous type. In this type, the herpes virus can affect many different internal organs including the liver, lungs, kidneys, and brain. There may or may not be vesicles on the skin. This type of infection is often fatal.

Herpes acquired in the period shortly after birth has symptoms similar to birth-acquired herpes.

Symptoms of birth-acquired herpes include:

• Bleeding easily
• Breathing difficulties
  • Blue appearance (cyanosis)
  • Flaring of the nostrils
  • Grunting
  • Rapid breathing (tachypnea)
  • Short periods without breathing (apneic episodes)
• Coma
• Enlarged liver and spleen
• Jaundice
• Kidney failure
• Lethargy
• Low body temperature (hypothermia)
• Poor feeding
• Seizures
• Shock
• Skin lesions, fluid-filled blisters
• Stress or anxiety