Fibrinogen Health Article

Definition

Fibrinogen is a protein produced by the liver. This protein helps stop bleeding by helping blood clots to form. A blood test can be done to tell how much fibrinogen you have in the blood.

Alternative Names

Serum fibrinogen; Plasma fibrinogen; Factor I; Hypofibrinogenemia test

How the test is performed

Blood is typically drawn from a vein, usually from the inside of the elbow or the back of the hand. The site is cleaned with germ-killing medicine (antiseptic). The health care provider wraps an elastic band around the upper arm to apply pressure to the area and make the vein swell with blood.

Next, the health care provider gently inserts a needle into the vein. The blood collects into an airtight vial or tube attached to the needle. The elastic band is removed from your arm.

Once the blood has been collected, the needle is removed, and the puncture site is covered to stop any bleeding.

In infants or young children, a sharp tool called a lancet may be used to puncture the skin and make it bleed. The blood collects into a small glass tube called a pipette, or onto a slide or test strip. A bandage may be placed over the area if there is any bleeding.

How to prepare for the test

There is no special preparation needed.

How the test will feel

When the needle is inserted to draw blood, some people feel moderate pain, while others feel only a prick or stinging sensation. Afterward, there may be some throbbing.

Why the test is performed

Your doctor may order this test if you have problems with blood clotting, particularly if you have excessive bleeding.

Normal Values

The normal range is 200-400 milligrams per deciliter (mg/dL).

Note: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.

What abnormal results mean

Abnormal results may be due to:

• Excessive fibrinogen use (as in disseminated intravascular coagulation)
• Fibrinolysis
• Hemorrhage
• Lack of fibrinogen production (acquired or from birth)

Additional conditions under which the test may be performed:

• Hemophilia A
• Hemophilia B
• Placenta abruptio