Infant of diabetic mother Health Article

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Reviewer Info: Deirdre O?Reilly, MD, MPH, Neonatologist, Division of Newborn Medicine, Children?s Hospital Boston and Instructor in Pediatrics, Harvard Medical School, Boston, Massachusetts. Review Provided by VeriMed Healthcare Network.; ADAM Health Illustrated Encyclopedia, 10/15/2007
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Definition

An infant of a diabetic mother is a baby born to a mother who has diabetes. The phrase specifically refers to a baby who is born to a mother who had persistently high blood sugar (glucose) levels during pregnancy.

Alternative Names

IDM

Causes, incidence, and risk factors

High blood sugar levels in pregnant women often have specific effects on their infants. Infants born to mothers who have diabetes are generally larger than other babies. They may have large organs, particularly the liver, adrenal glands, and heart.

These infants may have a hypoglycemic episode (low blood sugar) shortly after birth because of the increased insulin in the baby. Insulin is a substance that moves glucose from the blood into body tissues. This requires close monitoring of blood sugar levels in the infant.

Overall, there is an increased chance that mothers with poorly controlled diabetes will have a miscarriage or stillborn child. If the mother was diagnosed with diabetes before the pregnancy, her infant also has an increased risk of having birth defects if her disease is not well controlled.

Symptoms

The infant is usually large for gestational age. Other symptoms may include:

  • Blue or mottled skin color, rapid heart rate, rapid breathing (signs of heart failure)
  • Newborn jaundice
  • Poor feeding, lethargy, weak cry (signs of severe low blood sugar)
  • Puffy face
  • Reddish appearance
  • Tremors or shaking shortly after birth

Signs and tests

An ultrasound performed on the mother in the last few months of pregnancy shows a large for gestational age baby.

After birth, tests may show that the infant has low blood sugar and low blood calcium. An echocardiogram may show an abnormally large heart, which can lead to heart failure.

Treatment

All infants born to mothers with diabetes should be tested for low blood sugar (hypoglycemia), even if they have no symptoms.

If an infant had one episode of low blood sugar, tests to check blood sugars will be done over several days. This will continue until the infant's blood sugar remains stable with normal feedings.

Early feeding may prevent low blood sugar in mild cases. Persistent low blood sugar is treated with glucose given through a vein. Rarely, medications to treat other effects of diabetes on the infant are needed.

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