Meningitis - H. influenzae Health Article

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Reviewer Info: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Jatin M. Vyas, PhD, MD, Instructor in Medicine, Harvard Medical School, Assistant in Medicine, Division of Infectious Disease, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.; ADAM Health Illustrated Encyclopedia, 09/28/2008
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Definition

Haemophilus influenzae meningitis is a bacterial infection of the membranes covering the brain and spinal cord (meninges).

See also:

Alternative Names

H. influenzae meningitis; H. flu meningitis

Causes, incidence, and risk factors

H. influenzae meningitis is caused by Haemophilus influenzae bacteria. This bacteria should not be confused with the disease influenza, an upper respiratory infection caused by the influenza virus.

Before the Hib vaccine became available, H. influenzae was the leading cause of bacterial meningitis in children under 5 years of age. Since the introduction of the vaccine in the U.S., H. influenzae now occurs in less than 2 in 100,000 children. It still causes 5% - 10% of bacterial meningitis cases in adults.

H. influenzae meningitis may come after an upper respiratory infection. The infection usually spreads from the respiratory tract to the bloodstream, and then to the meninges. At the meninges, the bacteria produce infection and inflammation, causing serious illness and sometimes death.

Risk factors include:

Symptoms

  • Fever (in young infants the temperature may actually be below normal)
  • Irritability, poor feeding in infants
  • Nausea and vomiting
  • Pain in back when neck is bent forward and chin is brought toward chest (older children)
  • Sensitivity to light (photophobia)
  • Severe headache (older children)
  • Stiff neck or pain in neck
  • Unusual body positions

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