Premenstrual dysphoric disorder Health Article

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Table of Contents
Reviewer Info: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Susan Storck, MD, FACOG, Chief, Eastside Department of Obstetrics and Gynecology, Group Health Cooperative of Puget Sound, Redmond, Washington; Clinical Teaching Faculty, Department of Obstetrics and Gynecology, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.; ADAM Health Illustrated Encyclopedia, 12/31/2008
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Alternative Names

PMDD

Definition

Premenstrual dysphoric disorder (PMDD) is a condition marked by severe depression symptoms, irritability, and tension before menstruation. These symptoms are more severe than those seen with premenstrual syndrome (PMS).

Causes, incidence, and risk factors

The causes of PMS and PMDD have not been identified.

Hormone changes that occur during a woman's menstrual cycle appear to play a role.

PMDD affects between 3 - 8% of women during the years they are having menstrual periods. The condition is usually worse in younger women.

Seasonal affective disorder (SAD), major depression, anxiety, and similar disorders are seen in many women with this condition.

Other factors that may play a role include:

  • Alcohol abuse
  • Drinking large amounts of caffeine
  • Having a mother with a history of the disorder
  • Lack of exercise

Symptoms

The symptoms of PMDD are similar to those of PMS, but they are generally more severe and debilitating. Symptoms occur during the week just before menstrual bleeding and usually improve within a few days after the period starts.

Five or more of the following symptoms must be present:

  • Disinterest in daily activities and relationships
  • Fatigue or low energy
  • Feeling of sadness or hopelessness, possible suicidal thoughts
  • Feelings of tension or anxiety
  • Feeling out of control
  • Food cravings or binge eating
  • Mood swings marked by periods of teariness
  • Panic attack
  • Persistent irritability or anger that affects other peopleTrouble concentrating
  • Physical symptoms, such as bloating, breast tenderness, headaches, and joint or muscle pain
  • Sleep disturbances

Signs and tests

There are no physical examination findings or lab tests specific to the diagnosis of PMDD. A complete history, physical examination (including a pelvic exam), and psychiatric evaluation should be done to rule out other potential conditions.

Keeping a calendar or diary of symptoms can help women identify the most troublesome symptoms and the times they are likely to occur. This information may help the health care provider diagnose PMDD and determine the appropriate treatment.

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