Biguanides (Metformin) tell the liver to decrease its production of glucose, which lowers glucose levels in the bloodstream. Update Date: 06/17/2008Elizabeth H. Holt, MD, PhD, Assistant Professor of Medicine, Section of Endocrinology and Metabolism, Yale University. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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