Neutropenia is an abnormally low number of white blood cells called neutrophils. Neutrophils help the body fight infection. This article discusses neutropenia in infants.
Causes, incidence, and risk factors
Neutrophils are produced in the bone marrow and released into the bloodstream to travel to wherever they are needed. Low levels of neutrophils occur when the bone marrow cannot replace them as fast as needed. A very severe infection may also prevent the bone marrow from producing more neutrophils.
In babies, the most common cause of neutropenia is infection.
Occasionally, a non-sick infant will have a low neutrophil count for no apparent reason. Some disorders in the pregnant mother, such as preeclampsia, can also lead to neutropenia in infants.
Signs and tests
A small sample of the baby's blood will be sent to the laboratory for a complete blood count (CBS) and blood differential. A CBC reveals the number and type of red and white cells in the blood. The differential helps determine the number of different types of white blood cells in a blood sample.
Treatment
The source of the infection should be identified and treated.
In many cases, non-severe neutropenia goes away on its own as the bone marrow recovers and begins to produce enough white blood cells.
In rare cases when the neutrophil count is low enough to be life threatening, the following treatments may be recommended:
Medicines to stimulate white blood cell production
Agranulocytosis (1 image)(Doctor-Reviewed information)
Agranulocytosis means a failure of the bone marrow to make enough white blood cells (neutrophils. Bone marrow is the soft tissue inside bones that helps form blood cells. Reviewer: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and James R. Mason, MD, Oncologist, Director, Blood and Marrow Transplantation Program and Stem Cell Processing Lab, Scripps Clinic, Torrey Pines, California. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.Date: 07/11/2008
Sickle cell anemia (7 images)
Average Rating:
(Doctor-Reviewed information)
Sickle cell anemia is a disease passed down through families in which red blood cells form an abnormal crescent shape. (Red blood cells are normally shaped like a disc) Reviewer: Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.Date: 04/05/2009