Chronic kidney disease is the slow loss of kidney function over time. The main function of the kidneys is to remove wastes and excess water from the body.
Chronic kidney disease (CKD) slowly gets worse over time. In the early stages, there may be no symptoms. The loss of function usually takes months or years to occur. It may be so slow that symptoms do not occur until kidney function is less than one-tenth of normal.
The final stage of chronic kidney disease is called end-stage renal disease (ESRD). The kidneys no longer function and the patient needs dialysis or a kidney transplant.
Chronic kidney disease and ESRD affect more than 2 out of every 1,000 people in the United States.
Reflux nephropathy (in which the kidneys are damaged by the backward flow of urine into the kidneys)
Other kidney diseases
Chronic kidney disease leads to a buildup of fluid and waste products in the body. This condition affects most body systems and functions, including red blood cell production, blood pressure control, and vitamin D and bone health.
Symptoms
The early symptoms of chronic kidney disease often occur with other illnesses, as well. These symptoms may be the only signs of kidney disease until the condition is more advanced.
Acute kidney failure (1 image)(Doctor-Reviewed information)
Acute (sudden) kidney failure is the sudden loss of the ability of the kidneys to remove waste and concentrate urine without losing electrolytes.Reviewer: Parul Patel, MD, Private Practice specializing in Nephrology and Kidney and Pancreas Transplantation, Affiliated with California Pacific Medical Center, Department of Transplantation, San Francisco, CA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.Date: 07/11/2008
Peritonitis - dialysis associated (1 image)(Doctor-Reviewed information)
Dialysis-associated peritonitis is inflammation of the lining of the abdominal cavity (peritoneum) that occurs in someone who receives peritoneal dialysis.Reviewer: Daniel Levy, MD, PhD, Infectious Diseases, Greater Baltimore Medical Center, Baltimore, MD. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.Date: 08/20/2009
End-stage kidney disease (1 image)(Doctor-Reviewed information)
End-stage kidney disease is the complete, or almost complete failure of the kidneys to function. The kidneys can no longer remove wastes, concentrate urine, and regulate many other important body functions.Reviewer: Parul Patel, MD, Private practice specializing in Nephrology, Kidney and Pancreas Transplantation, affiliated with California Pacific Medical Center Department of Transplantation, San Francisco, CA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.Date: 08/12/2009
Renovascular hypertension (1 image)(Doctor-Reviewed information)
Renovascular hypertension is high blood pressure due to narrowing of the arteries that carry blood to the kidneys. See also: Atheroembolic renal disease; Hypertension; Malignant hypertension.Reviewer: Parul Patel, MD, Private Practice specializing in Nephrology and Kidney and Pancreas Transplantation, Affiliated with California Pacific Medical Center, Department of Transplantation, San Francisco, CA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.Date: 05/20/2009
Chronic bilateral obstructive uropathy (2 images)(Doctor-Reviewed information)
Chronic bilateral obstructive uropathy is a long-term blockage of urine flow from both kidneys. It is a slow blockage that gets worse over time. Bilateral means "both sides." See also: Chronic unilateral obstructive uropathy; Acute unilateral obst...Reviewer: Marc A. Greenstein, D.O., F.A.C.O.S. Urologist, Somerset Medical Center in Somerville, NJ. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.Date: 01/24/2008
Prerenal azotemia (2 images)(Doctor-Reviewed information)
Prerenal azotemia is an abnormally high level of nitrogen-type wastes in the blood.Reviewer: Parul Patel, MD, Private Practice specializing in Nephrology and Kidney and Pancreas Transplantation, affiliated with California Pacific Medical Center, Department of Transplantation, San Francisco, CA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.Date: 08/12/2009
Renal and urological disorders (2 images)(Doctor-Reviewed information)
Renal disorders refers to any disease of the kidneys. Urological disorders are diseases of the kidneys/urinary tract. This includes: Kidneys, ureters, urinary bladder, and urethra; Male reproductive organs including the testes, epididymis, vas def...Reviewer: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.Date: 08/09/2009