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Non-Hodgkin's lymphoma

Definition

Non-Hodgkin's lymphoma is cancer that starts in the lymphoid tissue. Such tissue makes up the lymph nodes, spleen, and other organs of the immune system.

Alternative Names

Lymphoma - non-Hodgkin's; Lymphocytic lymphoma; Histiocytic lymphoma; Lymphoblastic lymphoma; Cancer - non-Hodgkin's lymphoma

Causes, incidence, and risk factors

White blood cells called lymphocytes are found in lymph tissues. Most lymphomas start in a type of white blood cells called B lymphocytes.

For most patients, the cause of the cancer is unknown. However, lymphomas may develop in people with weakened immune systems. For example, after an organ transplant.

Non-Hodgkin's lymphoma is grouped, or staged, according to how fast the cancer spreads. The cancer may be low grade, intermediate grade or high grade. Burkitt's tumor is an example of a high-grade lymphoma. There are many different types of non-Hodgkin's lymphoma.

According to the American Cancer Society, a person has a 1 in 50 chance of developing non-Hodgkin's lymphoma. Most of the time, this cancer affects adults. However, children can get some forms of CLL. High-risk groups include those who have received an organ transplant or who have a weakened immune system (immunosuppression).

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Hodgkin's lymphoma (4 images) (Doctor-Reviewed information)
Hodgkin's lymphoma is a malignancy (cancer) of lymph tissue found in the lymph nodes, spleen, liver, and bone marrow. Reviewer: William Matsui, MD, Assistant Professor of Oncology, Division of Hematologic Malignancies, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD. Review provided by VeriMed Healthcare Network.Date: 05/03/2006

Primary lymphoma of the brain (1 image) (Doctor-Reviewed information)
Primary lymphoma of the brain is cancer that started in the brain. Reviewer: William Matsui, MD, Assistant Professor of Oncology, Division of Hematologic Malignancies, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD. Review provided by VeriMed Healthcare Network.Date: 09/27/2006

Burkitt lymphoma (2 images) (Doctor-Reviewed information)
Burkitt lymphoma is a very fast growing form of non-Hodgkin's lymphoma. Reviewer: Corey Cutler, MD, MPH, FRCP(C), Assistant Professor of Medicine, Harvard Medical School; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA. Review provided by VeriMed Healthcare Network.Date: 09/11/2006

B-cell leukemia/lymphoma panel (1 image) (Doctor-Reviewed information)
B-cell leukemia/lymphoma panel is a test that looks for specific proteins on the surface of white blood cells called B-lymphocytes. The proteins serve as?markers that may be helpful in the diagnosis of leukemia or lymphoma. Reviewer: James R. Mason, MD, Oncologist, Director, Blood and Marrow Transplantation Program and Stem Cell Processing Lab, Scripps Clinic, Torrey Pines, California. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.Date: 06/10/2008

T-cell count (1 image) (Doctor-Reviewed information)
T cells are a type of white blood cells (lymphocytes. They make up part of the immune system. T cells help the body fight diseases or harmful substances. A test can be done to measure the number of T cells in your blood. Reviewer: Frank A. Greco, M.D., Ph.D., Director, Biophysical Laboratory, The Lahey Clinic, Burlington, MA. Review provided by VeriMed Healthcare Network.Date: 10/15/2007

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