Several different types of cancer can occur in the stomach. The most common type is called adenocarcinoma, which starts from one of the common cell types found in the lining of the stomach. There are several types of adenocarcinoma. Because other types of gastric cancer occur much less frequently, this article focuses on adenocarcinoma of the stomach.
Adenocarcinoma of the stomach is a common cancer of the digestive tract worldwide, although it is relatively uncommon in the United States. It occurs most frequently in men over 40 years old. This form of gastric cancer is extremely common in Japan, Chile, and Iceland. The rate of most types of gastric adenocarcinoma in the United States has declined over the years. Experts think the decrease may be related to reduced intake of salted, cured, and smoked foods.
Diagnosis is often delayed bcause symptoms may not occur in the early stages of the disease, or because patients self-treat symptoms that may be common to other, less serious gastrointestinal disorders (bloating, gas, heartburn, and a sense of fullness).
Risk factors for gastric cancer are a family history of gastric cancer, Helicobacter pylori infection, blood type A, smoking, a history of pernicious anemia, a history of chronic atrophic gastritis, a condition of decreased gastric acid, and a prior history of an adenomatous gastric polyp.
Surgical removal of the stomach (gastrectomy) is the only curative treatment. Radiation therapy and chemotherapy may be beneficial. A recent study showed that for many patients, chemotherapy and radiation therapy given after surgery improve the chance of a cure.
Upper GI and small bowel series (5 images)(Doctor-Reviewed information)
An upper GI and small bowel series is a set of x-rays taken to examine the esophagus, stomach, and small intestine. See also: Barium enema Reviewer: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; George F. Longstreth, MD, Department of Gastroenterology, Kaiser Permanente Medical Care Program, San Diego, CA. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.Date: 11/02/2008
Stool guaiac test(Doctor-Reviewed information)
The stool guaiac test finds hidden (occult) blood in the stool (bowel movement. It is the most common form of fecal occult blood test (FOBT) in use today. Reviewer: Christian Stone, MD, Division of Gastroenterology, Washington University in St. Louis School of Medicine, St. Louis, MO. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.Date: 03/08/2008
Cancer - resources(Doctor-Reviewed information)
The following organizations are good resources for information on cancer: American Cancer Society - www.cancer.org; Cancer Care - www.cancercare.org; National Cancer Institute - www.cancer.gov. Reviewer: Jennifer K. Mannheim, CPNP, private practice, Seattle, Washington. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.Date: 10/18/2008
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