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Breast cancer

Definition

Breast cancer is a cancer that starts in the tissues of the breast.

There are two main types of breast cancer:

  • Ductal carcinoma starts in the tubes (ducts) that move milk from the breast to the nipple. Most breast cancers are of this type.
  • Lobular carcinoma starts in parts of the breast, called lobules, that produce milk.

In rare cases, breast cancer can start in other areas of the breast.

Many breast cancers are sensitive to the hormone estrogen. This means that estrogen causes the breast cancer tumor to grow. Such cancer is called estrogen receptor positive cancer or ER positive cancer.

Some women have what's called HER2-positive breast cancer. HER2 refers to a gene that helps cells grow, divide, and repair themselves. When cells have too many copies of this gene, cells -- including cancer cells -- grow faster. Experts think that women with HER2-positive breast cancer have a more aggressive disease and a higher risk of recurrence than those who do not have this type.

Alternative Names

Cancer - breast; Carcinoma - ductal; Carcinoma - lobular

Causes, incidence, and risk factors

Over the course of a lifetime, one in eight women will be diagnosed with breast cancer.

Risk factors you cannot change include:

Age and gender -- Your risk of developing breast cancer increases as you get older. The majority of advanced breast cancer cases are found in women over age 50.

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Mastectomy (1 image) (Doctor-Reviewed information)
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A mammogram is an x-ray picture of the breasts. It is used to find tumors and to help tell the difference between non-cancerous (benign) and cancerous (malignant) disease. Reviewer: Benjamin Taragin, M.D., Department of Radiology, Columbia Presbyterian Medical Center, New York, NY. Review Provided by VeriMed Healthcare Network.Date: 10/17/2007

Breast ultrasound (1 image) (Doctor-Reviewed information)
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Breast biopsy (4 images) (Doctor-Reviewed information)
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