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Rheumatoid arthritis

Rheumatoid arthritis

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Rheumatoid arthritis

Definition

Rheumatoid arthritis (RA) is a long-term disease that causes inflammation of the joints and surrounding tissues. It can also affect other organs.

Alternative Names

RA; Arthritis - rheumatoid

Causes, incidence, and risk factors

The cause of RA is unknown. It is considered autoimmune disease. The body's immune system normally fights off foreign substances, like viruses. But in an autoimmune disease, the immune system confuses healthy tissue for foreign substances. As a result, the body attacks itself.

RA can occur at any age. Women are affected more often than men.

RA usually affects joints on both sides of the body equally. Wrists, fingers, knees, feet, and ankles are the most commonly affected. The course and the severity of the illness can vary considerably. Infection, genes, and hormones may contribute to the disease.

Symptoms

The disease usually begins gradually with:

  • Fatigue
  • Morning stiffness (lasting more than 1 hour)
  • Widespread muscle aches
  • Loss of appetite
  • Weakness

Eventually, joint pain appears. When the joint is not used for a while, it can become warm, tender, and stiff.

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Juvenile rheumatoid arthritis (Doctor-Reviewed information)
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Caplan syndrome is swelling (inflammation) and scarring of the lungs in people with rheumatoid arthritis who have been exposed to mining dust, such as coal, silica, or asbestos. Reviewer: Allen J. Blaivas, DO, Pulmonary, Critical Care, and Sleep Medicine, Department of Veteran Affairs, VA New Jersey Health Care System, East Orange, NJ. Review provided by VeriMed Healthcare Network.Date: 08/10/2007

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