Nutrition Health Article

NUTRITION

Few subjects are more important to public health than food. One of the major ways in which humans interact with their environment is through our food. The science of nutrition has developed through the study of the components of foods that are required to sustain life and to maintain health. Improper diet can cause disease if important nutrients are missing from the diet, and inappropriate dietary practices can increase the risk of certain diseases.

Essential nutrients are substances that must be in the human diet to support life. These essential nutrients include vitamins, inorganic elements, essential amino acids, essential fatty acids, and a source of energy, and water. A lack of a nutrient or an insufficient amount of a nutrient can result in a deficiency disease that can be life threatening in extreme cases. The essential nutrients are widely distributed in foods and most people can obtain sufficient amounts of them if they consume a varied diet.

ELEMENTS OF HUMAN NUTRITION

Energy. Most of the food consumed is used by the body to supply energy. The body is able to digest and absorb into the blood stream components of carbohydrates, fats, and protein that can be metabolized by the body to release energy. Energy is used to maintain body temperature, support metabolic processes, and to support physical activity. People are generally in a state of energy balance, that is, they consume as much energy as they use to support their bodies and daily living. They tend to gain weight if they are in positive energy balance, or lose weight if they take in less than they expend. Most excess energy is stored by the body as fat. Energy needs are usually expressed in kilocalories, but in much of the world's scientific literature, energy expenditure is expressed in joules or kilojoules (1 kilocalorie equals 4.184 kilojoules).

The energy expended by the body when at rest is quite constant between individuals and can be

Table 1

estimated quite closely by prediction equations that take into account age, sex, and body weight. The resting metabolic weight of a 70-kilogram (154-lb.) man, for example, is estimated to be 1750 kilocalories per day, and for a 58-kilogram (128-lb.) woman, 1350 kilocalories per day. The total daily energy needs are related to the amount of physical activity expended in the course of everyday life. A person whose life style involves light amounts of activity may have a total energy expenditure of about one and one-half times their resting metabolic rate, while a person who is engaged in very intense physical activity may expend over twice as much energy as their resting metabolic rate in the course of twenty-four hours. Exercise can increase the metabolic rate considerably, depending on the type and duration of the activity. The amount of energy expended by certain types of physical activity is shown in Table 1.

Protein. The principal structural components of body soft tissues are proteins, which are made by the body from amino acids. The amino acids along with the nucleic acids are the principle nitrogen-containing components of the body and of most foods. The enzymes that regulate most body processes are also proteins. The body can synthesize many of the amino acids needed for protein syntheses, but some amino acids must be obtained from the proteins in the diet. The dietary essential amino acids for humans are threonine, valine, leucine, isoleucine, methionine, lysine, histidine, and tryptophan. Two others can only be formed from essential amino acids: tryosine from phenylalanine, and cystine from methionine. Human dietary protein requirements are quite modest. An adult man of average weight is estimated to need about sixty-three grams of protein per day, while an average woman is estimated to need about fifty grams. The protein must supply the essential amino acids required by humans and sufficient total nitrogen to allow syntheses of the other amino acids required for protein synthesis.

Fats. Fats are synthesized from carbohydrates, but the body is unable to make certain fatty acids, which are components of fats. These essential fatty acids, notably linoleic and linolenic acid, must be supplied by dietary fats. Fats that are solid at room temperature, such as butter or lard, usually contain high amounts of saturated fatty acids such as palmitic or stearic acid. Fats that are liquid at room temperature such as vegetable oils are higher in unsaturated fatty acids, which include oleic acid as well as the linoleic and linolenic acid. Fat is the most concentrated source of energy available to humans, supplying about nine kilocalories per gram of dietary fat, compared to four kilocalories per gram of carbohydrate and protein. Fat is also the principal storage form of energy in the body.

Vitamins. Vitamins are a diverse group of dietary essentials that have important functions in the body. The vitamins known to be required by humans are listed in Table 2. Many of them are components of co-enzymes, molecules that are required for some enzymes to carry out certain metabolic processes. Others, such as vitamin E and vitamin C, act as antioxidants, protecting body components from damage from oxygen needed by the body for metabolism. Some are more like hormones, such as vitamin D, which regulates the absorption of calcium from the intestine and the formation of bones. Vitamin D can actually be formed by the action of ultraviolet light from the sun on vitamin D precursors found in the skin, but since this synthesis may not be sufficient at times, humans need a dietary source of vitamin D. Vitamin A is a component of visual pigments in the eye that respond to light stimuli and are essential for sight.

A deficiency of a vitamin may result in a characteristic deficiency disease related to the body function affected by the lack of the vitamin. Vitamin D deficiency can cause soft bones in children, a condition called rickets; vitamin A deficiency

Table 2

may cause night blindness and even blindness in its more severe form. Many of the vitamins have multiple functions in the body, and deficiency diseases can be severely debilitating in severe cases. Vitamins are required in very small amounts by the body. Only a few micrograms of vitamin B₁₂is required each day, while vitamin C requirements may be from sixty to one hundred milligrams per day.

Inorganic elements. Humans also require several inorganic elements as components of the diet. The inorganic elements known to be required by humans are listed in Table 2. These elements may have a structural function, such as calcium and phosphorus, which are needed for bone synthesis, or they may have a catalytic function similar to some of the vitamins. They are required for the action of many enzymes in the body. Sodium and potassium are essential for fluid balance. Iodine is an essential component of thyroxin, the hormone produced by the thyroid gland. Some of the inorganic elements are required in extremely small quantities, only micrograms per day, while other elements may be needed in higher amounts. Soils vary in their content of some of the trace elements, and plants grown in some areas may be deficient in an essential element. This has been true for iodine, where a deficiency is still observed in many areas of the world, and selenium, where geographically based human deficiency disease has been observed.