Oxymorphone Hydrochloride Rectal suppository Health Article

Generic name(s):

Oxymorphone Hydrochloride Rectal suppository

Brand name(s):

Numorphan HCl, Opana, Opana ER

What is this medicine?

OXYMORPHINE (ox i MOR feen) is a pain reliever. It is used to treat moderate to severe pain.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• brain tumor
• drug abuse or addiction
• head injury
• if you frequently drink alcohol containing drinks
• intestinal disease
• kidney disease
• kyphoscoliosis
• liver disease
• lung disease, asthma, or breathing problems
• seizures
• an unusual or allergic reaction to oxymorphone, codeine, other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I use this medicine?

This medicine is for rectal use only. Do not take by mouth. Wash your hands before and after use. Take off the foil wrapping. Wet the tip of the suppository with cold tap water to make it easier to use. Lie on your side with your lower leg straightened out and your upper leg bent forward toward your stomach. Lift upper buttock to expose the rectal area. Apply gentle pressure to insert the suppository completely into the rectum, pointed end first. Hold buttocks together for a few seconds. Remain lying down for about 15 minutes to avoid having the suppository come out. Do not use more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Patients over 65 years old may have a stronger reaction and need a smaller dose.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

• alcohol or medicines that contain alcohol

This medicine may also interact with the following medications:

• antihistamines for allergy, cough and cold
• atropine
• benzodiazepines
• certain medicines for bladder problems like oxybutynin, tolterodine
• certain medicines for Parkinson's disease like benztropine, trihexyphenidyl
• certain medicines for stomach problems like dicyclomine, hyoscyamine
• certain medicines for travel sickness like scopolamine
• ipratropium
• medicines for depression, anxiety, or psychotic disturbances
• medicines for pain like pentazocine, buprenorphine, butorphanol, nalbuphine, tramadol, and propoxyphene
• medicines for sleep
• muscle relaxants
• naltrexone
• phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.