Pentamidine Isethionate Solution for injecti... Health Article

Generic name(s):

Pentamidine Isethionate Solution for injection

Brand name(s):

Nebupent, Pentam 300

What is this medicine?

PENTAMIDINE (pen TAM i deen) is an anti-infective drug. It is used to treat Pneumocystis carinii pneumonia (PCP).

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• diabetes
• heart problems
• kidney disease
• pancreatitis
• an unusual or allergic reaction to pentamidine, other medicines, foods, dyed, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I use this medicine?

This medicine is for injection into a muscle or infusion into a vein. It is usually given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 4 months old for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

• amoxapine
• arsenic trioxide
• certain antibiotics like clarithromycin, erythromycin, gatifloxacin, gemifloxacin, grepafloxacin, moxifloxacin, sparfloxacin
• cidofovir
• cisapride
• droperidol
• haloperidol
• levomethadyl
• maprotiline
• medicines for malaria like chloroquine and halofantrine
• medicines to control heart rhythm
• methadone
• phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
• pimozide
• ranolazine
• tricyclic antidepressants like amitriptyline, imipramine, nortriptyline, and others
• zalcitabine, ddC
• ziprasidone

This medicine may also interact with the following medications:

• abarelix
• alfuzosin
• certain antibiotics like gentamicin, levofloxacin, mefloquine, tobramycin, vancomycin
• cyclobenzaprine
• diuretics
• ganciclovir
• foscarnet
• medicines for depression, anxiety, or psychotic disturbances
• medicines for diabetes
• medicines for nausea like dolasetron, ondansetron, palonosetron
• medicines for sleep during surgery
• medicine to numb skin
• octreotide
• some bowel prep medicines
• some medicines for cancer
• tacrolimus
• vardenafil

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine. Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

This medicine can change your blood sugar levels. High blood sugar can cause more thirst and more urine passed, loss of appetite, fruity breath odor, and drowsiness. Low blood sugar can cause hunger, pale skin, headache, anxiety, chills or cold sweats, and shakiness. Call your doctor or health care professional if you think you have a problem with your blood sugar level.