abacavir-lamivudine-zidovudine (oral)

Brand name(s):

abacavir/lamivudine/zidovudine, Trizivir

What is the most important information I should know about abacavir-lamivudine-zidovudine (Trizivir)?

Stop using this medication and call your doctor at once if you have any of these signs of an allergic reaction: fever; rash; nausea, vomiting, diarrhea, stomach pain; general tiredness, body aches; shortness of breath, cough, sore throat. Once you have had an allergic reaction to this medication, you must never use it again.

Read the Warning Card that comes with this medication, and carry it with you at all times so you will know the symptoms of allergic reaction to watch for.

Do not allow this medicine to run out completely before you get your prescription refilled. If you miss several doses, you could have a dangerous or even fatal allergic reaction when you start taking the medicine again. If you stop taking this medication for any reason, talk to your doctor before you start taking the medication again.

What is abacavir-lamivudine-zidovudine (Trizivir)?

Abacavir-lamivudine-zidovudine is an antiviral medication. It is in a group of human immunodeficiency virus (HIV) medicines called reverse transcriptase inhibitors. This medication helps keep the HIV virus from reproducing in the body.

This medication is used to treat HIV, which causes the acquired immunodeficiency syndrome (AIDS). This medication is not a cure for HIV or AIDS.

This medication may also be used for purposes other than those listed in this medication guide. This medication should not be given to people who weigh less than 90 pounds.

What should I discuss with my healthcare provider before taking abacavir-lamivudine-zidovudine (Trizivir)?

Do not take this medicine if you have ever had an allergic reaction to abacavir. Tell your doctor if you have had an allergic reaction to any medicine that contains abacavir, such as Combivir, Epzicom, or Ziagen. Once you have had an allergic reaction to abacavir, you must never use it again. This medication may cause lactic acidosis (the build up of lactic acid in the body). Lactic acidosis symptoms can start slowly and gradually get worse. Symptoms include unusual muscle pain and weakness, trouble breathing, fast or uneven heart rate, nausea, vomiting, stomach pain, and numbness or cold feeling in your arms or legs. Contact your doctor at once if you have any of these symptoms, even if they are only mild. Early signs of lactic acidosis generally get worse over time and this condition can be fatal.

Your name may need to be listed on an abacavir patient registry when you start using this medication.

Before taking this medication, tell your doctor if you have liver or kidney disease. You may not be able to use this medication or you may need a dosage adjustment or special tests during treatment. FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. HIV can be passed to the baby if the mother is not properly treated during pregnancy. Take all of your HIV medicines as directed to control your infection while you are pregnant. You should not breast-feed while you are using this medication. Women with HIV or AIDS should not breast-feed at all. Even if your baby is born without HIV, you may still pass the virus to the baby in your breast milk.

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