abacavir-lamivudine-zidovudine (oral) Health Article

You may have other serious side effects that may not be signs of an allergic reaction. Continue using this medicine and call your doctor if you have any of these side effects:

• stomach pain, low fever, lost appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

• muscle pain or weakness, numb or tingly feeling, and nausea with vomiting;

• fever, chills, body aches, flu symptoms;

• white patches or sores inside your mouth or on your lips.

Less serious side effects may be more likely to occur, such as:

• changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and trunk);

• sleep problems or strange dreams;

• headache, depression, anxiety; or

• mild diarrhea.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect abacavir-lamivudine-zidovudine (Trizivir)?

Before taking this medication, tell your doctor if you are using any of the following drugs:

• methadone (Methadose, Dolophine);

• ribavirin (Copegus, Rebetron, Virazole);

• interferon (Rebetron, Roferon, Intron, Alferon, Infergen, Avonex, Rebif, Betaseron, Actimune);

• sulfa drugs such as Bactrim or Septra;

• doxorubicin (Adriamycin);

• ganciclovir (Cytovene);

• emtricitabine (Emtriva, Truvada);

• abacavir (Ziagen);

• abacavir and lamivudine (Epzicom);

• lamivudine and zidovudine (Combivir); or

• these other HIV medicines - lamivudine (3TC, Epivir), stavudine (Zerit), or zidovudine (Retrovir).

If you are using any of these drugs, you may not be able to take Trizivir, or you may need dosage adjustments or special monitoring during treatment.

There may be other drugs not listed that can affect Trizivir. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist has more information about abacavir-lamivudine-zidovudine (Trizivir) written for health professionals that you may read.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.