acetaminophen and pseudoephedrine

Brand name(s):

acetaminophen-pseudoephedrine, Allerest No Drowsiness, Bayer Select Decongestant, Benadryl Allergy Sinus Headache, Contac Sinus, Excedrin Sinus, Ornex, Sine-Off Maximum Strength, Sinutab Regular Strength, Sudafed Cold and Sinus, Theraflu Sinus, Tylenol Cold Infants, Tylenol Sinus Maximum Strength

What is the most important information I should know about acetaminophen and pseudoephedrine?

Always ask a doctor before giving cough or cold medicine to a child. Death can occur from the misuse of cough or cold medicine in very young children. Do not take more of this medication than is recommended. An overdose of acetaminophen can cause damage to your liver. Do not use any other over-the-counter cough, cold, allergy, or pain medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you take to see if it contains acetaminophen or pseudoephedrine. If you drink more than three alcoholic beverages per day, do not take this medication without your doctor's advice.

What is acetaminophen and pseudoephedrine?

Acetaminophen is a pain reliever and fever reducer.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of acetaminophen and pseudoephedrine is used to treat stuffy nose, sinus congestion, and pain or fever casued by the common cold. Pseudoephedrine also treats congestion of the tubes that drain fluid from your inner ears, called the eustachian (yoo-STAY-shun) tubes.

Acetaminophen and pseudoephedrine may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking acetaminophen and pseudoephedrine?

Do not use this medication if you are allergic to acetaminophen or pseudoephedrine, or to other decongestants, diet pills, stimulants, or ADHD medications. Do not use this medication if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take a decongestant before the MAO inhibitor has cleared from your body.

Before taking acetaminophen and pseudoephedrine, tell your doctor if you are allergic to any drugs, or if you have:

If you have any of these conditions, you may not be able to use acetaminophen and pseudoephedrine, or you may need a dosage adjustment or special tests during treatment.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Acetaminophen and pseudoephedrine may pass into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Artifically-sweetened liquid forms of cough-and-cold medications may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.

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