hydrochlorothiazide and aliskiren

Brand name(s):

aliskiren-hydrochlorothiazide, Tekturna HCT

What is the most important information I should know about hydrochlorothiazide and aliskiren?

Do not use this medication without telling your doctor if you are pregnant. Hydrochlorothiazide and aliskiren may cause injury and even death to the unborn baby if you take it during the second and third trimesters of pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment. Do not use potassium supplements or salt substitutes while you are taking hydrochlorothiazide and aliskiren, unless your doctor has told you to. There are many other medicines that can interact with hydrochlorothiazide and aliskiren. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

It may take up to 4 weeks for this medication to control your blood pressure. Keep using this medication even if you feel fine. High blood pressure often has no symptoms.

What is hydrochlorothiazide and aliskiren?

Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Aliskiren is an anti-hypertensive (blood pressure lowering) medication. It works by decreasing substances in the body that narrow blood vessels and raise blood pressure.

The combination of hydrochlorothiazide and aliskiren is used to treat high blood pressure (hypertension).

Hydrochlorothiazide and aliskiren may also be used for other purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking hydrochlorothiazide and aliskiren?

You should not use this medication if you are allergic to aliskiren (Tekturna) or hydrochlorothiazide (Carozide, Diaqua, Ezide HCTZ, HydroDiuril, Microzide, and others), or if you are unable to urinate.

Before using hydrochlorothiazide and aliskiren, tell your doctor if you are allergic to any drugs, or if you have:

low or high levels of potassium in your blood;
kidney disease;
liver disease;
gout;
lupus;
diabetes; or
an allergy to sulfa drugs.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

FDA pregnancy category D. This medication can cause harm to an unborn baby. Hydrochlorothiazide and aliskiren may cause injury and even death to the unborn baby if you take it during the second and third trimesters of pregnancy. Do not use hydrochlorothiazide and aliskiren without your doctor's consent if you are pregnant. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment. It is not known whether hydrochlorothiazide and aliskiren passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

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