ambrisentan

Brand name(s):

Letairis

What is the most important information I should know about ambrisentan?

This medication can cause birth defects. Do not use if you are pregnant. Tell your doctor right away if you miss a menstrual period during treatment with ambrisentan. Use two reliable forms of birth control together while you are taking the medication and for at least 1 month after your treatment ends.

You will probably be required to take a pregnancy test before you start using this medicine, to make sure you are not pregnant. You may also be re-tested each month during your treatment.

Ambrisentan can cause severe liver problems. Symptoms include nausea, stomach pain, itching, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). Call your doctor at once if you have any of these symptoms. Your liver function will need to be tested before you start taking ambrisentan, and again each month during your treatment. Do not stop taking ambrisentan without first talking to your doctor. You may need to use less and less before you stop the medication completely.

Ambrisentan is available only under a special program called LEAP (Letairis Education and Access Program). You must be registered in the program and sign agreements to use birth control and undergo pregnancy and blood testing as required by the program. Read all program brochures and agreements carefully.

What is ambrisentan?

Ambrisentan prevents thickening of the blood vessels, especially those in the lungs and heart. Ambrisentan also lowers blood pressure in your lungs, helping your heart pump blood more efficiently.

Ambrisentan is used to treat pulmonary arterial hypertension (PAH). It improves your ability to exercise and prevents your condition from getting worse.

Ambrisentan may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking ambrisentan?

Your should not use this medication if you are allergic to ambrisentan, or if you are pregnant.

Before taking ambrisentan, tell your doctor if you have liver disease or if you have ever had liver problems caused by other medications.

Ambrisentan can cause severe liver problems. Symptoms include nausea, stomach pain, itching, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). Call your doctor at once if you have any of these symptoms. Your liver function will need to be tested before you start taking ambrisentan, and again each month during your treatment. FDA pregnancy category X. This medication can cause birth defects. Do not use ambrisentan if you are pregnant. Tell your doctor right away if you miss a menstrual period during treatment with ambrisentan. Use two reliable forms of birth control while you are taking this medication and for at least 1 month after your treatment ends.

You will probably be required to take a pregnancy test before you start using this medicine, to make sure you are not pregnant. You may also be re-tested each month during your treatment.

It is not known whether ambrisentan passes into breast milk or if it could harm a nursing baby. Do not take this medication without telling your doctor if you are breast-feeding a baby.

Ambrisentan may lower a man's sperm count and could affect fertility (your ability to have children).

Page: 1 2 Next >

Use of this Web site constitutes acceptance of our Terms and Conditions of Use and Privacy Policy.