acetaminophen, diphenhydramine, and phenylep... Health Article

What other drugs will affect acetaminophen, diphenhydramine, and phenylephrine?

Do not take acetaminophen, diphenhydramine, and phenylephrine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A drug interaction could occur, leading to serious side effects.

Urine glucose tests for diabetics may produce false results while taking acetaminophen. Talk to your doctor if you are diabetic and you notice changes in your glucose levels while taking acetaminophen, diphenhydramine, and phenylephrine.

Do not take other over-the-counter cough, cold, allergy, diet, pain, or sleep medicines while taking acetaminophen, diphenhydramine, and phenylephrine without first talking to your doctor or pharmacist. Other medications may also contain diphenhydramine, phenylephrine, acetaminophen, or other similar drugs, and you may accidentally take too much of these medicines.

Acetaminophen, diphenhydramine, and phenylephrine may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, other antihistamines, pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Dangerous sedation, dizziness, or drowsiness may occur if acetaminophen, diphenhydramine, and phenylephrine is taken with any of these medications.

Drugs other than those listed here may also interact with acetaminophen, diphenhydramine, and phenylephrine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Where can I get more information?

Your pharmacist has additional information about acetaminophen, diphenhydramine, and phenylephrine written for health professionals that you may read.

What does my medication look like?

Acetaminophen, diphenhydramine, and phenylephrine is available over-the-counter under several brand and generic names. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.