hydrochlorothiazide and candesartan

Brand name(s):

candesartan-hydrochlorothiazide, Atacand HCT

What is the most important information I should know about candesartan and hydrochlorothiazide?

Do not use this medication without telling your doctor if you are pregnant. Candesartan and hydrochlorothiazide may cause injury and even death to the unborn baby if you take it during the second and third trimesters of pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment. Candesartan and hydrochlorothiazide can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can lower your blood pressure and may increase some of the side effects of candesartan and hydrochlorothiazide.

What is candesartan and hydrochlorothiazide?

Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Candesartan is in a group of drugs called angiotensin II receptor antagonists. Candesartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.

The combination of candesartan and hydrochlorothiazide is used to treat high blood pressure (hypertension).

Candesartan and hydrochlorothiazide may also be used for other purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking candesartan and hydrochlorothiazide?

You should not use this medication if you are allergic to candesartan or hydrochlorothiazide (Carozide, Diaqua, Ezide HCTZ, HydroDiuril, Microzide, and others), or if you are unable to urinate.

Before using candesartan and hydrochlorothiazide, tell your doctor if you are allergic to any drugs, or if you have:

kidney disease;
liver disease;
congestive heart failure;
low or high levels of potassium in your blood;
asthma or allergies;
high cholesterol or triglyceride levels;
gout;
lupus;
diabetes; or
an allergy to sulfa drugs.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

FDA pregnancy category D. This medication can cause harm to an unborn baby. Candesartan and hydrochlorothiazide may cause injury and even death to the unborn baby if you take it during the second and third trimesters of pregnancy. Do not use candesartan and hydrochlorothiazide without your doctor's consent if you are pregnant. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment. It is not known whether candesartan and hydrochlorothiazide passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

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