carbinoxamine

Brand name(s):

Carbinoxamine PD, Cordron NR, Histex I/E, Histex PD, Histex Pd 12, Palgic, Pediatex, Pediatex 12

What is the most important information I should know about carbinoxamine?

Always ask a doctor before giving a cold or allergy medicine to a child, even if the medicine label provides dosing instructions for children. Death can occur from the misuse of cough and cold medicines in very young children. Do not give this medication to a child younger than 2 years old, even if the medicine label provides dosing instructions for children in this age group. Deaths have been reported in children under 2 years old who had received carbinoxamine, although it has not been determined that carbinoxamine was the cause of these deaths. Talk with your doctor about other FDA-approved products available for use in young children with cold or allergy symptoms. Do not use carbinoxamine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take carbinoxamine before the MAO inhibitor has cleared from your body. Carbinoxamine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of carbinoxamine.

Call your doctor if you have a fever, or if your symptoms get worse or do not improve after taking this medicine for 7 days.

What is carbinoxamine?

Carbinoxamine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Carbinoxamine is used to treat sneezing, runny nose, itchy or watery eyes, hives, skin rash, itching, and other symptoms of allergies and the common cold.

Carbinoxamine may also be used for other purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking carbinoxamine?

Do not give this medication to a child younger than 2 years old, even if the medicine label provides dosing instructions for children in this age group. Deaths have been reported in children under 2 years old who had received carbinoxamine, although it has not been determined that carbinoxamine was the cause of these deaths. Talk with your doctor about other FDA-approved products available for use in young children with cold or allergy symptoms. Do not use carbinoxamine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take carbinoxamine before the MAO inhibitor has cleared from your body. Do not use this medication if you are allergic to carbinoxamine, or if you are breast-feeding.

Before taking this medication, tell your doctor if you are allergic to any drugs, or if you have:

glaucoma;
a stomach ulcer;
a blockage in your stomach or intestines;
an enlarged prostate or urination problems;
overactive thyroid;
heart disease, high blood pressure; or
asthma.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take carbinoxamine.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether carbinoxamine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Older adults may be more likely to have side effects from this medicine.

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