carbinoxamine, methscopolamine, and pseudoep... Health Article

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Doctor-reviewed Information, Multum Drug Directory, 2006

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Generic name(s):

carbinoxamine, methscopolamine, and pseudoephedrine

Brand name(s):

carbinoxamine/methscopolamine/pseudoephedrine, Pannaz, Pannaz S

What is the most important information I should know about carbinoxamine, methscopolamine, and pseudoephedrine?

Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Do not use a cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cold medicine before the MAO inhibitor has cleared from your body. Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains an antihistamine or decongestant.

What is carbinoxamine, methscopolamine, and pseudoephedrine?

Carbinoxamine and methscopolamine are antihistamines that reduce the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Carbinoxamine, methscopolamine, and pseudoephedrine is used to treat sneezing, runny or stuffy nose, itchy or watery eyes, hives, skin rash, itching, and other symptoms of allergies and the common cold.

Carbinoxamine, methscopolamine, and pseudoephedrine may also be used for purposes other than those listed here.

What should I discuss with my healthcare provider before taking carbinoxamine, methscopolamine, and pseudoephedrine?

Do not give this medication to a child younger than 2 years old, even if the label has dosing instructions for children this young. Death can occur from the use of carbinoxamine in very young children. Talk with your doctor about other FDA-approved products available for young children with cold or allergy symptoms. Do not use a cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cold medicine before the MAO inhibitor has cleared from your body.

Before taking this medication, tell your doctor if you are allergic to carbinoxamine, methscopolamine, or pseudoephedrine, or if you have:

epilepsy or another seizure disorder;
peripheral vascular disease such as Raynaud's syndrome;
thyroid problems;
asthma, emphysema, or chronic obstructive pulmonary disease (COPD);
diabetes;
glaucoma;
an ulcer or an obstruction in the stomach;
an enlarged prostate or urination problems;
heart disease or high blood pressure;
kidney disease; or
liver disease.

If you have any of the conditions listed above, you may not be able to take carbinoxamine, methscopolamine, and pseudoephedrine, or you may require a dosage adjustment or special tests during treatment.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Carbinoxamine, methscopolamine, and pseudoephedrine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

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