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dasatinib Health Article

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Table of Contents
Doctor-reviewed Information, Multum Drug Directory, 2006
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Generic name(s):

dasatinib

Brand name(s):

Sprycel

What is the most important information I should know about dasatinib?

Do not use this medication without your doctor's consent if you are pregnant. It could cause harm to the unborn baby. Use an effective form of birth control, and tell your doctor if you become pregnant during treatment. Do not use dasatinib if you have heart disease or a heart rhythm disorder, or if you have a personal or family history of "Long QT syndrome."

Before using dasatinib, tell your doctor if you have liver disease or low levels of potassium or magnesium in your blood.

Do not crush, chew, or break a dasatinib tablet. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time.

There are many other medicines that can interact with dasatinib. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

Dasatinib can lower the blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. To be sure your blood cells do not get too low, your blood will need to be tested on a regular basis. It is important that you not miss any scheduled visits to your doctor.

Avoid contact with people who have colds, the flu, or other contagious illnesses. Contact your doctor immediately if you develop signs of infection.

What is dasatinib?

Dasatinib is a cancer medication that slows the growth and spread of cancer cells in the body.

Dasatinib is used to treat chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL) when other cancer treatments have not been effective.

Dasatinib may also be used for other purposes not listed in this medication guide.

What should I discuss with my health care provider before taking dasatinib?

Do not use dasatinib if you have:
  • heart disease or a heart rhythm disorder; or

  • a personal or family history of "Long QT syndrome."

Before using dasatinib, tell your doctor if you have:

  • liver disease; or

  • low levels of potassium or magnesium in your blood.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

FDA pregnancy category D. This medication can cause harm to an unborn baby. Do not use dasatinib without telling your doctor if you are pregnant. Tell your doctor if you become pregnant during treatment. Use an effective form of birth control while you are using this medication. It is not known whether dasatinib passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Taking dasatinib may affect your ability to have children whether you are a man or a woman. Talk to your doctor about your specific risk.

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