eletriptan

Brand name(s):

Relpax

What is the most important information I should know about eletriptan?

Eletriptan can cause serious side effects on the heart, including heart attack or stroke. Although these side effects are rare, do not use this medication if you have a history of heart disease, angina (chest pain), blood circulation problems, ischemic bowel disease, severe or uncontrolled high blood pressure, or history of a heart attack or stroke.

Before using eletriptan, tell your doctor if you have coronary artery disease, or risk factors for coronary artery disease (such as diabetes, menopause, smoking, being overweight, having high blood pressure or high cholesterol, having a family history of coronary artery disease, being older than 40 and a man, or being a woman who has had a hysterectomy).

Do not use eletriptan within 24 hours after taking almotriptan (Axert), naratriptan (Amerge), frovatriptan (Frova), sumatriptan (Imitrex), rizatriptan (Maxalt), zolmitriptan (Zomig), or ergot medicine such as methysergide (Sansert), ergotamine (Ergomar, Ergostat, Cafergot, Ercaf, Wigraine), dihydroergotamine (D.H.E. 45, Migranal Nasal Spray), ergonovine (Ergotrate), methylergonovine (Methergine). Do not use eletriptan within 72 hours after taking ketoconazole (Nizoral), itraconazole (Sporanox), nefazodone (Serzone), clarithromycin (Biaxin), troleandomycin (Tao), ritonavir (Norvir), or nelfinavir (Viracept). Before taking eletriptan, tell your doctor if you are also taking an antidepressant such as citalopram (Celexa), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft), or venlafaxine (Effexor).

Eletriptan will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks.

After taking a eletriptan tablet, you must wait two (2) hours before taking a second tablet. Do not take more than 80 mg of eletriptan in 24 hours.

What is eletriptan?

Eletriptan is a headache medicine. It is believed to work by narrowing the blood vessels around the brain. Eletriptan also reduces substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms.

Eletriptan is used to treat migraine headaches.

Eletriptan will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks.

Eletriptan may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before using eletriptan?

Do not use this medication if you are allergic to eletriptan, or if you have:

a history of heart disease, angina (chest pain), blood circulation problems, or history of a heart attack or stroke;
severe liver disease;
ischemic bowel disease;
severe or uncontrolled high blood pressure; or
a headache that is not like other headaches you have had.

Do not use eletriptan within 24 hours after taking any of the following medicines:

almotriptan (Axert), naratriptan (Amerge), frovatriptan (Frova), sumatriptan (Imitrex), rizatriptan (Maxalt), or zolmitriptan (Zomig); or
ergot medicine such as methysergide (Sansert), ergotamine (Ergomar, Ergostat, Cafergot, Ercaf, Wigraine), dihydroergotamine (D.H.E. 45, Migranal Nasal Spray), ergonovine (Ergotrate), methylergonovine (Methergine).

Do not use eletriptan within 72 hours after taking any of the following medicines:

ketoconazole (Nizoral), itraconazole (Sporanox);
nefazodone (Serzone);
clarithromycin (Biaxin), troleandomycin (Tao); or
ritonavir (Norvir), nelfinavir (Viracept).

Before using eletriptan, tell your doctor if you have:

high blood pressure;
liver disease;
coronary artery disease (or risk factors that include diabetes, menopause, smoking, being overweight, having high blood pressure or high cholesterol, having a family history of coronary artery disease, being older than 40 and a man, or being a woman who has had a hysterectomy).

If you have any of these conditions, you may need a dose adjustment or special tests to safely take eletriptan.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Eletriptan can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. This medicine should not be given to anyone younger than 18 years old.

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