enalapril and felodipine

Brand name(s):

enalapril-felodipine, Lexxel

What is the most important information I should know about enalapril and felodipine?

Do not use this medication without telling your doctor if you are pregnant or planning a pregnancy. Enalapril and felodipine could cause birth defects in the baby if you take the medication during pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment.

Vomiting, diarrhea, or heavy sweating can cause you to become dehydrated. This can lead to very low blood pressure, electrolyte disorders, or kidney failure while you are taking enalapril and felodipine. Drink plenty of water each day while you are taking this medication.

What is enalapril and felodipine?

Enalapril is in a group of drugs called ACE inhibitors. ACE stands for angiotensin converting enzyme.

Felodipine is in a group of drugs called calcium channel blockers. It works by relaxing the muscles of your heart and blood vessels.

The combination of enalapril and felodipine is used to treat high blood pressure (hypertension). It is usually given after other blood pressure medications have been tried without successful treatment of hypertension.

Enalapril and felodipine may also be used for other purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking enalapril and felodipine?

Do not use this medication if you are allergic to enalapril and felodipine or to any other ACE inhibitor, such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik).

Before using enalapril and felodipine, tell your doctor if you are allergic to any drugs, or if you have:

kidney disease (or if you are on dialysis);
liver disease;
heart disease or congestive heart failure;
low sodium levels in your body (hyponatremia);
diabetes; or
a history of stroke or heart attack.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

FDA pregnancy category D. Do not use this medication without telling your doctor if you are pregnant or planning a pregnancy. Enalapril and felodipine could cause birth defects in the baby if you take the medication during pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment. Enalapril and felodipine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

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