hydrochlorothiazide and metoprolol Health Article

• swelling, rapid weight gain, feeling short of breath, even with mild exertion;

• fast, slow, or uneven heartbeat;

• easy bruising or bleeding;

• numbness or tingly feeling in your hands or feet;

• feeling weak, drowsy, restless, or light-headed;

• nausea, vomiting, dry mouth, extreme thirst, headache, confusion, hallucinations, seizure (convulsions);

• increased urination, leg discomfort, muscle pain or weakness or limp feeling;

• urinating less than usual or not at all;

• fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or

• upper stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

• diarrhea, constipation, upset stomach;

• dizziness, spinning sensation;

• sore throat, body aches;

• blurred vision; or

• ringing in your ears.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

What other drugs will affect hydrochlorothiazide and metoprolol?

Many drugs can interact with hydrochlorothiazide and metoprolol. Below is just a partial list. Tell your doctor if you are using:

• insulin or diabetes medicine you take by mouth;

• colestipol (Colestid) or cholestyramine (Prevalite, Questran);

• theophylline (Elixophyllin, Respbid, Slo-Bid, Theo-Dur, Uniphyl, and others);

• steroids (prednisone and others);

• HIV or AIDS medicine such as ritonavir (Norvir);

• an antidepressant such as bupropion (Wellbutrin, Zyban), fluoxetine (Prozac), or paroxetine (Paxil);

• an antibiotic such as rifampin (Rifadin, Rifamate, Rimactane) or terbinafine (Lamisil);

• anti-malaria medication such as hydroxychloroquine (Plaquenil);

• medicine to treat psychiatric or mood disorders, such as chlorpromazine (Thorazine), haloperidol (Haldol), lithium (Lithobid), or thioridazine (Mellaril);

• NSAIDs (non-steroidal anti-inflammatory drugs) such as aspirin, ibuprofen (Motrin, Advil), diclofenac (Voltaren), etodolac (Lodine), indomethacin, naproxen (Aleve, Naprosyn), and others; or

• other heart or blood pressure medications such as clonidine (Catapres), propafenone (Rythmol), quinidine (Quinidex, Quin-Release Quin-G) reserpine, or verapamil (Calan, Covera, Isoptin, Verelan).

This list is not complete and there may be other drugs that can interact with hydrochlorothiazide and metoprolol. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about hydrochlorothiazide and metoprolol.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.