hydrochlorothiazide and quinapril

Brand name(s):

hydrochlorothiazide-quinapril, Accuretic

What is the most important information I should know about hydrochlorothiazide and quinapril?

Do not use this medication if you are unable to urinate.

You should not use this medication if you are allergic to any other ACE inhibitor, such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), ramipril (Altace), or trandolapril (Mavik).

Before taking hydrochlorothiazide and quinapril, tell your doctor if you have kidney disease (or are on dialysis), liver disease, congestive heart failure, gout, lupus, diabetes, or an allergy to sulfa drugs.

Quinapril can cause birth defects in the baby if you take the medication during pregnancy. Do not use hydrochlorothiazide and quinapril without telling your doctor if you are pregnant or planning a pregnancy. Avoid the regular use of salt substitutes in your diet, and do not take potassium supplements while taking hydrochlorothiazide and quinapril, unless your doctor has told you to.

Some things can cause your blood pressure to get too low. This includes vomiting, diarrhea, heavy sweating, heart disease, dialysis, a low-salt diet, or taking other diuretics (water pills). Follow your doctor's instructions about the type and amount of liquids you should drink while taking hydrochlorothiazide and quinapril. Tell your doctor if you have a prolonged illness that causes diarrhea or vomiting.

What is hydrochlorothiazide and quinapril?

Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Quinapril is in a group of drugs called ACE inhibitors. ACE stands for angiotensin converting enzyme. Quinapril lowers blood pressure and also relieves symptoms of fluid retention.

The combination of hydrochlorothiazide and quinapril is used to treat hypertension (high blood pressure).

Hydrochlorothiazide and quinapril may also be used for other purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking hydrochlorothiazide and quinapril?

Do not use this medication if you are allergic to hydrochlorothiazide or quinapril, or if you are unable to urinate.

You should not use this medication if you are allergic to other ACE inhibitor, such as benazeprin (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), ramipril (Altace), or trandolapril (Mavik).

Before taking hydrochlorothiazide and quinapril, tell your doctor if you have:

kidney disease (or if you are on dialysis);
liver disease;
congestive heart failure;
gout;
lupus;
diabetes; or
an allergy to sulfa drugs.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take hydrochlorothiazide and quinapril.

FDA pregnancy category D. Do not use this medication without telling your doctor if you are pregnant or planning a pregnancy. Quinapril could cause birth defects in the baby if you take the medication during pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment. Hydrochlorothiazide can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

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