idarubicin Health Article

Generic name(s):

idarubicin

Brand name(s):

Idamycin, Idamycin PFS

What is the most important information I should know about idarubicin?

Idarubicin should only be administered under the supervision of a qualified healthcare provider experienced in the use of cancer chemotherapeutic agents.

Serious side effects have been reported with the use of idarubicin including: allergic reactions (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); severe heart damage with prolonged use; decreased bone marrow function and blood problems (extreme fatigue; easy bruising or bleeding; black, bloody or tarry stools; fever or chills; or signs of infection); severe nausea, vomiting, diarrhea, and loss of appetite; and others.Talk to your doctor about the possible side effects from treatment with idarubicin.

What is idarubicin?

Idarubicin is a cancer (antineoplastic) medication. Idarubicin interferes with the growth of cancer cells and slows their growth and spread in the body.

Idarubicin is used to treat a type of blood cancer (acute myeloid leukemia -AML) in adults .

Idarubicin may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before using idarubicin?

Do not use idarubicin without first talking to your doctor if you have

• kidney disease;
• liver disease;

• heart disease;

• poor bone marrow function;

• received radiation therapy that encompassed the heart; or

• previously received treatment with doxorubicin (Adriamycin, Rubex), doxorubicin liposomal (Doxil), daunorubicin (Cerubidine), daunorubicin liposomal (Daunoxome), idarubicin (Idamycin), or mitoxantrone (Novantrone).

The use of idarubicin may be dangerous if you have any of the conditions listed above.

Idarubicin is in the FDA pregnancy category D. This means that idarubicin is known to be harmful to an unborn baby. Do not use idarubicin without first talking to your doctor if you are pregnant or could become pregnant during treatment. Discuss with your doctor the appropriate use of birth control during treatment with idarubicin if necessary. Because of the potential for serious side effects in a nursing infant, breast-feeding should be avoided during treatment with idarubicin. The safety and effectiveness of idarubicin in children has not been established.

How should I use idarubicin?

Idarubicin should only be administered under the supervision of a qualified healthcare provider experienced in the use of cancer chemotherapeutic agents.

Your doctor will determine the correct amount and frequency of treatment with idarubicin depending upon the type of cancer being treated and other factors. Talk to your doctor if you have any questions or concerns regarding the treatment schedule.

Your doctor will probably want you to have regularly scheduled blood tests and other medical evaluations during treatment with idarubicin to monitor progress and side effects.

Skin accidentally exposed to idarubicin should be rinsed thoroughly with soap and warm water.

Your healthcare provider will store idarubicin as directed by the manufacturer. If you are storing idarubicin at home, follow the directions provided by your healthcare provider.

What happens if I miss a dose?

Contact your doctor if you miss a dose of idarubicin.

What happens if I overdose?

If for any reason an overdose of idarubicin is suspected, seek emergency medical attention or contact your healthcare provider immediately.

Symptoms of a idarubicin overdose tend to be similar to side effects caused by the medication, although often more severe.

What should I avoid while using idarubicin?

Skin accidentally exposed to idarubicin should be rinsed thoroughly with soap and warm water.

Do not receive "live" vaccines during treatment with idarubicin. Administration of a live vaccine may be dangerous during treatment with idarubicin.