midodrine Health Article

What other drugs will affect midodrine?

Before taking midodrine, talk to your doctor if you are taking any other medicines especially any of the following:

• an alpha adrenergic blocker such as alfuzosin (Uroxatral), doxazosin (Cardura), guanadrel (Hylorel), prazosin (Minipress), or terazosin (Hytrin);

• flecainide (Tambocor);

• cimetidine (Tagamet, Tagamet HB) or ranitidine (Zantac, Zantac 75);

• digoxin (Lanoxin);

• metformin (Glucophage);

• fludrocortisone (Florinef);

• triamterene (Dyrenium, Dyazide, Maxzide);

• drugs that stimulate alpha-adrenergic receptors such as pseudoephedrine, phenylephrine, ephedrine, or dihydroergotamine;

• quinidine (Quinaglute, Quinidex, Quin-Release); or

• procainamide (Procan SR, Procanbid, Pronestyl).

You may not be able to take midodrine, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

Other prescription and over-the-counter medicines may cause an increase in blood pressure, which may be dangerous when taken with midodrine. Do not take any other prescription or over-the-counter medicines or herbal products especially cough, cold, or allergy products, weight loss products, asthma or respiratory medicines, migraine headache medicines, heart or blood pressure medicines, irregular heartbeat medicines, or antidepressants without first talking to your doctor.

Drugs other than those listed here may also interact with midodrine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Where can I get more information?

Your pharmacist has additional information about midodrine written for health professionals that you may read.

What does my medication look like?

Midodrine is available with a prescription under the brand name ProAmantine. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

• ProAmantine 2.5. mg-white, round, scored tablets

• ProAmantine 5 mg-orange, round, scored tablets

• ProAmantine 10 mg-blue, round, scored tablets

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.