progesterone

Brand name(s):

First Progesterone MC10, First Progesterone MC5, Prometrium

What is the most important information I should know about progesterone?

Do not use this medication without telling your doctor if you are pregnant. It could cause harm to the unborn baby. Use an effective form of birth control, and tell your doctor if you become pregnant during treatment. Some forms of this medication may contain peanut oil. Do not use progesterone without telling your doctor if you have a peanut allergy. Using progesterone can increase your risk of blood clots, stroke, heart attack, or breast cancer. Do not use this medication if you have any of the following conditions: a history of stroke or blood clot, circulation problems, severe liver disease, a hormone-related cancer such as breast or uterine cancer, abnormal vaginal bleeding, or if you have recently had an incomplete or "missed" abortion.

Progesterone is sometimes given for only a short period of time, such as 6 to 12 days at a time during each menstrual cycle. Following your dosing schedule is very important for this medication to be effective. Try not to miss any doses.

Progesterone can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

What is progesterone?

Progesterone is a female hormone important for the regulation of ovulation and menstruation.

Progesterone is used to cause menstrual periods in women who have not yet reached menopause but are not having periods due to a lack of progesterone in the body. Progesterone is also used to prevent overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy.

Progesterone may also be used for other purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using progesterone?

Some forms of this medication may contain peanut oil. Do not use progesterone without telling your doctor if you have a peanut allergy. Do not use progesterone if you have:

a history of stroke or blood clot;
circulation problems;
a hormone-related cancer such as breast or uterine cancer;
abnormal vaginal bleeding;
severe liver disease;
if you are pregnant; or
if you have recently had an incomplete or "missed" abortion.

Before using this medication, tell your doctor if you have any of the following conditions. You may need a dose adjustment or special tests to safely use progesterone.

high blood pressure, heart disease, congestive heart failure;
migraines,
asthma;
kidney disease;
seizures or epilepsy;
a history of depression; or
diabetes.

Do not use progesterone without your doctor's consent if you are pregnant. Tell your doctor if you become pregnant during treatment. Use an effective form of birth control while you are using this medication. Progesterone can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

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