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1. Factor II deficiency
(Trust Mark: Doctor-Reviewed)
Factor II deficiency is a blood clotting (coagulation) problem that occurs when there is a lack of a substance (prothrombin) that is needed for blood to clot. Reviewer: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc. Expand your search to include all of U.S. News
2. MedlinePlus Medical Encyclopedia: Factor V deficiency
Factor V deficiency is an inherited abnormal blood coagulation disorder caused by a deficiency of the plasma. Prolonged prothrombin time. In the inherited form of Factor V deficiency, a family history of a bleeding disorder is a risk factor. http://www.nlm.nih.gov/medlineplus/ency/article/000550.htm
3. Vitamin K: Vitamins: Merck Manual Home Edition
The damaged liver may be unable to synthesize prothrombin and other clotting factors even after vitamin K injections. Disorders that interfere with fat absorption can reduce the absorption of vitamin K and cause vitamin K deficiency. http://www.merck.com/mmhe/sec12/ch154/ch154e.html
4. Blood Coagulation
Prothrombin* and Xa* are Gla-less forms of prothrombin and Xa, synthesized in the absence of vitamin K. 3) Factor XIIa triggers clotting via the sequential activation of factors XI, IX, X, and II (prothrombin) Activation of factor XII is not... http://tollefsen.wustl.edu/projects/coagulation/coagulation.html |
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