1. Angioedema  (Trust Mark: Doctor-Reviewed)
Angioedema is a swelling, similar to hives, but the swelling is beneath the skin rather than on the surface. The hives are called welts. It is also possible to have angioedema without hives. See also: Hereditary angioedema • Reviewer: David C. Dugdale, III., MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Stuart I. Henochowicz, MD, FACP, Associate Clinical Professor of Medicine, Division of Allergy, Immunology, and Rheumatology, Georgetown University Medical School. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

2. Hereditary angioneurotic edema  (Trust Mark: Doctor-Reviewed)
Hereditary angioneurotic edema (HANE) is a nonsex-linked (autosomal) dominant disease that results from mutations in a gene responsible for producing one of the proteins responsible for human immunity. This disease is also known as hereditary angioe...• Author: Paul A. Johnson